They found that the ELISPOT assay was useful in the diagnosis of ITP and was more sensitive than the MAIPA assay (90% versus 66%).9,10 So in our study, we chose to detect anti-GPIIb/IIIa and anti-GPIb antibody producing B cells by the ELISPOT assay for the common existence of the antibodies in patients with primary ITP and the high sensitivity of the assay. The gene discussed is ITGA2B; the disease is autoimmune thrombocytopenic purpura.