Presence of antibodies, one of the criteria defining APS was IgG 49.7%, IgM 33.5% and lupus anticoagulant 27.0% from Saudi Arabia.5 Prevalence of APS secondary to SLE is 25.38% in India.6 The APS is a systemic autoimmune disorder associated with hypercoagulabilty, pregnancy morbidity, thrombocytopenia, and thromboembolic phenomenon. This evidence concerns the gene CD40LG and autoimmune polyendocrinopathy.