PPARG and metabolic disease: Figure 8b shows a plot with the distribution of DisGeNET scores of PPARG-associated diseases from curated sources by MeSH class. The two best-represented disease classes are Neoplasms (12 diseases), and Nutritional and Metabolic Diseases (11 diseases). The latter category includes the top three highest scoring diseases, in agreement with the role of PPARG in nutrient levels sensing and the modulation of lipid and glucose metabolism (34).