Although not yet fully defined, it is known that the expression of apolipoprotein AI or ABCA1 in hepatocytes can reduce hepatic steatosis, decreasing the storage of lipids in the hepatocytes by transporting the lipids and also by reducing the oxidative stress of the endoplasmic reticulum, which further favors the diminishment of steatosis [79]. The gene discussed is ABCA1; the disease is steatosis.