KLK3 and cancer: The mean age and PSA at the time of the PBx in the cancer group were higher than those of the non-cancer group (66.5 ± 7.4 vs. 62.3 ± 9.4 years, P < 0.001 and 5.8 ± 2.1 vs. 5.2 ± 2.0 ng/ml, P < 0.001, respectively).