The hyperglycemia and hypoinsulinemia of F1OB males compared to F1Con males observed in biweekly samples was also present in fasted samples taken prior to the IVGTT conducted at the end of the feeding challenge (82.59 ± 1.25 vs 71.97 ± 1.10 mg/dl; P < 0.0001 and 17.90 ± 3.10 vs 30.26 ± 2.09 μIU/ml; P < 0.01 glucose and insulin respectively). Here, INS is linked to Hypoinsulinemia.