While Treg cell depletion partially restores the ability of T cells from Ag+GILT-/-Tg mice to induce vitiligo, Treg cell-depleted melanoma-specific T cells from these animals induce disease with diminished severity and delayed onset in comparison to vitiligo caused by T cells from Ag-GILT+/+Tg mice [22]. Here, RENBP is linked to vitiligo.