All in all, the MeCP2 oscillations described here may play an important role in the sleeping disturbances that, in autistic diseases including Rett syndrome, involve alterations of the MeCP2 function [48, 49] and appear to also be frequent in other neurologic diseases such as Parkinson’s, Alzheimer’s, and schizophrenia or anxiety-related disorders [50]. Here, MECP2 is linked to atypical Rett syndrome.