Interestingly and consistent with the ELISA data, the percentages of IL-10-producing CD4+ cells were not different between WT and Bam32-/- mice, although the absolute numbers were higher than those from WT mice (Fig 2G, 2L and 2M), which could be due to higher splenomegaly during the late stage of infection (see Fig 1D). Here, CD4 is linked to Splenomegaly.