In contrast, infected Bam32-/- mice showed significantly reduced serum levels of trypanosome-specific IgG (Fig 4B), IgG1 (Fig 4C) and IgG2a (Fig 4D) starting from day 28 (IgG and IgG1) or 48 (IgG2a) post-infection, which corresponds to the onset of uncontrolled parasitemia in these mice. The gene discussed is DAPP1; the disease is parasitic infectious disease.