As shown in Table 1, the OS and DFS were worse for women with the following characteristics: younger age than 40 years, aged 60 or older, postmenopausal, larger tumor size and positive lymph nodes, advanced TNM stage and histological and nuclear grade, ER-, PR-, and HR-negative, and HR+ HER2+, HR- HER2+, and HR- HER2- subtypes compared to the HR+ HER2- subtype (P<0.05). Here, ESR1 is linked to neoplasm.