In this study we investigated the effects of classic glucocorticoids versus the effects of compound A on the ability of peripheral blood mononuclear cells (PBMCs) (Table 1) as well as inferior turbinate tissue (Table 2) to respond to a challenge with Staphylococcus aureus–derived enterotoxin B protein (SEB), previously used in an established model to investigate human nasal polyposis. The gene discussed is SETBP1; the disease is Nasal polyposis.