As is described in the European GWAS analysis, SNP rs870142 locates in the interval between STX18 and MSX1. STX18 is a synaptosome associated protein receptor that functions in the endoplasmic reticulum, intermediate compartment, and cis-Golgi vesicle trafficking and may not be a candidate for ASD risk [14]. This evidence concerns the gene MSX1 and atrial septal defect.