In contrast to the other proinflammatory markers, the cardio-protective biomarker adiponectin was significantly lower in persons with than those without agoraphobia after adjustment for covariates (models 1–5; Table 3 and Table 8; β = -0.053 (95%-CI -0.101 to -0.005; p = 0.032)). The gene discussed is ADIPOQ; the disease is agoraphobia.