On the one hand, AGR3 was described as a marker of favourable prognosis in serous ovarian cancer [26], whereas a recent publication on the other hand indicated a pro-oncogenic potential for AGR3 demonstrating the mediation of cisplatin resistance by AGR3 in a H1299 cell line xenograft mouse model [29]. The gene discussed is AGR3; the disease is ovarian serous adenocarcinoma.