IGF1R and cancer: IGF1R and ITGB3 participate in important cellular signaling pathways involved in cancer development and both have previously been implicated as prognostic factors in ovarian cancer [15,16,17,18]; since PRKCZ plays a role in the regulation of various cellular signal pathways [2], we sought to determine whether PRKCZ can affect the regulation of IGF1R and ITGB3 in ovarian cancer.