Among a number of melanoma markers being considered in the literature (https://www.aacc.org/SiteCollectionDocuments/NACB/LMPG/tumor/chp3L_melanoma.pdfTable 2b Tissue tumor markers), five proteins exhibited substantial expression in our experiment (presence in at least 40% of the samples in either approach): S100B, ICAM, NDKA (NM23), MUC18 (MCAM), PMEL (GP100). The gene discussed is PMEL; the disease is neoplasm.