BCR and posterior cortical atrophy: To assess the diagnostic and prognostic value of pre-surgical serum miRNAs, we profiled the levels of 21 miRNAs in 50 men with BPH and 100 men with PCa, 50 of whom had 100% Gleason grade 3 tumors and no BCR and 50 men with tumors with 30–90% Gleason grade 4 or 5 and variable BCR.