Some studies found that KCNJ10 gene rs1130183 (Arg271Cys) was associated with seizure resistance in groups of patients with both focal and generalized epilepsy[11, 13].It is also suggested that a missense variant (Thr262Ser) in KCNJ10 was likely to be candidate gene for seizure[12]. This evidence concerns the gene KCNJ10 and generalized epilepsy.