TNF and Parkinson disease: To establish PITX3eGFP/w neurons as a tool for modeling neurodegeneration in PD we tested the effects of the neurotoxin MPP+, as well as two neuroinflammatory mediators: TNF, as well as prostaglandin E2 [PGE2, which is elevated in response to MPP+ (Wang et al., 2005)] on mature PITX3eGFP/w neurons.