We applied the iPLEX system (Sequenom) and PCR-RFLP measurements to successfully evaluate 25 SNPs at TBX21, GATA3, Rorc and Foxp3 genes in an independent cohort containing 406 BD patients, 401 VKH syndrome patients and 613 healthy controls. This evidence concerns the gene TBX21 and Vogt-Koyanagi-Harada disease.