However, the association of these four transcriptional factors with BD and VKH syndrome has not yet been addressed and was therefore the aim of our study whereby we explored the association of two genetic variants including CNVs as well as SNPs of TBX21, GATA3, Rorc and Foxp3 in the pathogenesis of uveitis via a two-stage case control study. The gene discussed is TBX21; the disease is uveitis.