This indirectly suggests that ATF3 exerts promoting effects on the development and invasion process of glioblastoma, although the most relevant target genes and the corresponding signaling pathways through which ATF3 promotes glioblastoma cells to invade, and factors regulating ATF3 in glioblastoma during the invasion process have not yet been fully elucidated. Here, ATF3 is linked to glioblastoma.