More important, all these miRNAs had been reported to repress EMT and tumor invasion by targeting the 3′-UTR of ZEB1, ZEB2, and ZNF217, etc. Thus, we used microarray analysis to compare the miRNA expression level between the TR SKBR-3 and WT SKBR-3, we found 98 up-regulated and 73 down-regulated miRNAs in TR SKBR-3 cells. Here, ZEB1 is linked to neoplasm.