They conducted a thorough clinical classification of 2,360 variants (as of February 2014) in the DNA mismatch repair (MMR) genes MLH1 (MIM #120436), MSH2 (MIM #609309), MSH6 (MIM #600678), and PMS2 (MIM #600259) that had been identified in patients suspected of having Lynch syndrome [Thompson et al., 2013b]. Here, MLH1 is linked to Lynch syndrome.