Loss-of-function mutations of VPS13A (vacuolar protein sorting-associated protein 13A), the gene encoding chorein, lead to chorea-acanthocytosis (CA), an autosomal recessive genetic disease [4-9] characterized by progressive hyperkinetic movement disorder, cognitive dysfunction, behavioral abnormalities, chronic hyperkalemia and variable acanthocytosis of red blood cells [5, 10]. The gene discussed is VPS13A; the disease is chorea-acanthocytosis.