Given that A549 and H1650 are epithelial cell lines, reflected by the expression of E-Cadherin, while H460 is a mesenchymal cell line without detectable E-Cadherin expression (Supplementary Figures 4A-B), these data indicate that XPC is able to inhibit proliferation and migration of NSCLC cells with an epithelial phenotype. The gene discussed is CDH1; the disease is non-small cell lung carcinoma.