Data mining, using cBioportal [19] of The Cancer Genome Atlas (TCGA) database [20], which contains 1062 samples of invasive breast carcinomas, indicated that sortilin is altered in 7.2% of breast tumors with 5 cases of amplification, 2 homozygous deletions, 4 mutations, 59 mRNA up regulations, and 8 mRNA down regulations (data not shown). The gene discussed is SORT1; the disease is breast neoplasm.