In agreement with this, in exosomes from serum of control and ALL patient peripheral blood (TSG101-positive microvesicles with an average size distribution of 92 ± 2.6 nm and 98 ± 0.4 nm respectively on Nanosight), Galectin-3 was not readily detectable (results not shown). The gene discussed is LGALS3; the disease is acute lymphoblastic leukemia.