Although there was a significant difference in uNGAL levels between no AKI, transient AKI and intrinsic AKI, this difference did not remain when patients were stratified according to severity of sepsis (sepsis with or without shock) and to tertiles of CRP or APACHE II score increase, except for sNGAL in the highest CRP tertile where a significant difference between AKI and no AKI could be found. The gene discussed is CRP; the disease is acute kidney injury.