YES1 and neoplasm: Similar to what was observed for pFAK Y861, Yes expression was increased by 2.3 fold in PC3-P lymph node metastases compared to PC3-P primary tumors (p < 0.001) (Fig. 7C, compare panel 1 to panel 3) with no further increase in expression of Yes in PC3 Mig-3 lymph node metastasis relative to PC3 Mig-3 primary tumor (Fig. 7C; compare panel 3 to panel 4; quantification of IHC, Fig. 7D bottom panel).