TNF and sarcoidosis: Indeed, on the basis of the review of literature, the most responsive patients to therapy with infliximab appear to be those with extrapulmonary disease, with involvement of skin, nervous system, bone, and ocular disease; it would be interesting to study these patients with 99mTc-infliximab scintigraphy in order to effectively assess the presence of TNFα in other extrapulmonary tissues affected by sarcoidosis.