Intron 1 of the gene is the only one associated with obesity, multiple FTO gene variants being at that location which is correlated to this disorder: rs9939609, rs17817449, rs1421085, rs9930506, rs8050136, rs9751812, rs9751812 and other 25 validated SNPs [23-26]. The gene discussed is FTO; the disease is obesity due to melanocortin 4 receptor deficiency.