As an oncogene, c-MYC is closely correlated with metastasis of NSCLC [4], and there is (are) a binding site(s) for c-MYC in BCYRN1 promoter area, based on the online search results (http://www.sabiosciences.com/chipqpcrsearch.php?gene=BCYRN1&species_id=0&factor=c-Myc&ninfo=n&ngene=n&nfactor=n; http://liweilab.genetics.ac.cn/tm/gene.php?st=gn&gn=c-Myc-binding%20protein&gi=618&ti=9606). The gene discussed is BCYRN1; the disease is non-small cell lung carcinoma.