In this study, a higher percentage of Bcl-2 immunoexpression was observed in ameloblast-like tumor cells, confirming the high Bcl-2 protein immunoexpression of either most or a considerable number of ameloblastic tumor cells; our results are in agreement with published data from other authors and could be considered as a type of inhibition of the mechanisms of cellular apoptosis induction [24, 30, 31]. The gene discussed is BCL2; the disease is neoplasm.