Expression of some ER-associated molecules, such as HERPUD1 and NDRG1, was reduced in PCa samples from patients (Segawa et al, 2002), and GRP78 expression levels were associated with greater risk of PCa recurrence and worse survival (Pootrakul et al, 2006; Daneshmand et al, 2007). This evidence concerns the gene NDRG1 and posterior cortical atrophy.