LDHA and pancreatic adenocarcinoma: The European Society for Medical Oncology (ESMO) has established Practice Guidelines that suggest that enhanced clonogenic growth of ALDH+ cancer cells has an important role in the long-term outcome of patients diagnosed with pancreatic adenocarcinoma by mediating or even stimulating cancer dissemination throughout the abdominal cavity and resistance to chemotherapy with 5-fluorouracil (5-FU) or gemcitabine [21].