Data showed that STZ-induced diabetic rats exhibited increased levels of oxidative stress detected by higher levels of ROS and lipid peroxidation, increased levels of apoptotic cells associated with upregulation of proapoptotic Bax and downregulation of antiapoptotic Bcl-2 in testes, and increased levels of microcirculation impairment demonstrated by decreased levels of blood flow velocity and VEGF, whereas SCU significantly reversed those hyperglycemia-induced actions. The gene discussed is BCL2; the disease is Hyperglycemia.