It is noted that CTNNBL1 is connected with ITGAV by SPP1; previous studies have proved that CTNNBL1 has a close relation with regulation of apoptosis, regulation of programmed cell death, and membrane-enclosed lumen [11], which implies that the extracellular matrix module may regulate the ovarian cancer progression by regulating apoptosis, main cell death patterns in ovarian cancer cells. This evidence concerns the gene SPP1 and ovarian cancer.