In accordance with these reports, a cross-sectional analysis at our nephrology outpatient unit revealed that among 288 long-term kidney transplant recipients with a mean eGFR of 38 ± 14 mL/min/1.73 m2 at 10 ± 5 years after transplantation, 10% were hypercalcemic and had parathyroid hormone levels above the target range as recommended by The Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guidelines (Steindl G. and Borchhardt K., unpublished data, 2006). The gene discussed is PTH; the disease is medical procedure.