Her medical history included a mild form of MCTD diagnosed in 2006 (Sharp's syndrome with anti-DNA and anti-RNP antibodies), three previous episodes of angioneurotic oedema, two recent episodes of septicaemia (Streptococcus agalactiae and pneumoniae), and a tuboovarian abscess treated by laparoscopic drainage 2 months before. Here, RNPC3 is linked to mixed connective tissue disease.