For miR-125b, overexpression of the target genes in HCC tumor tissues has been found for B-Cell CLL/Lymphoma 2 (BCL2), v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2/3 (ERBB2/3), sirtuin7 (SIRT7), v-ets avian erythroblastosis virus E26 oncogene homolog 1 (ETS1), myeloid cell leukemia sequence 1 (Mcl-1), interleukin 6 receptor (IL6R), and Lin-28 Homolog B (LIN28B). This evidence concerns the gene BCL2 and hepatocellular carcinoma.