Previously, we demonstrated that the highly pathogenic avian influenza virus A/VN/1203/04 was neurotropic and induced both an inflammatory pathology as well as induction of a number of parkinsonian pathologies including tremor, loss of tyrosine hydroxylase (TH) positive dopaminergic neurons in the SN and increased phosphorylation of alpha-synuclein [9,18]. Here, SNCA is linked to Tremor.