AGER and neoplasm: Based on this model, RAGE expression levels (hazard ratio (HR) = 2.143; 95% confidence interval (95% CI) = 1.357–3.383; P = 0.001) and tumor invasion (HR = 11.209; 95% CI = 1.297–96.874; P = 0.028) were confirmed as independent prognostic factors (Table 3).