As mentioned above, SASP treatment induced a much higher number of uniquely altered genes in the dually infected BC-1 (KSHV+/EBV+) cells than in BCBL-1 and BCP-1 (both of which are KSHV+/EBVneg), suggesting that complex interactions between these co-existent oncogenic herpesviruses may influence the outcome of SASP treatment. Here, OPN1SW is linked to breast cancer.