For instance, xCT is expressed on some Burkitt's lymphoma cell-lines such as BL-41 and BJAB (both KSHVneg/EBVneg), AKATA (KSHVneg/EBV+) and on some diffuse large cell lymphoma (DLCL) cell-lines such as CRL2631 (KSHVneg/EBVneg), and inhibition of xCT by SASP also induced significant apoptosis in BL-41 lymphoma cells expressing high levels of xCT [5]. The gene discussed is SLC7A11; the disease is Burkitt lymphoma.