For example, SRXN1 (Sulfiredoxin-1), which is upregulated in all three SASP-treated PEL cell lines (Table 1) is involved in proliferation inhibition of acute myeloid leukemia mediated by Maesopsin 4-O-beta-D-glucoside, a natural compound isolated from the leaves of Artocarpus tonkinensis) [21]. Here, SRXN1 is linked to acute myeloid leukemia.