BMI1 and cancer: We next examined the correlation between our 32-gene score and 6 different gene signatures previously reported to reflect angiogenesis and outcome in a range of cancers: a VEGF signature [25], a vascular invasion signature [26], a wound response signature [27], a hypoxia gene signature [28], a TGFβ gene-response signature of human epithelial cells [29] and a BMI-1 driven stemness related gene signature [30].