A number of oncogenic signaling molecules and pathways are involved in c-Src-mediated cancer cell invasion and migration, including the chicken tumor virus No.10 (CT10) regulator of kinase (Crk)-associated substrate (p130Cas), Abelson murine leukemia viral oncogene homolog 1 (ABL1, also known as c-Abl), paxillin, focal adhesion kinase (FAK), as well as PI3K-Akt, Ras-Raf-MEK-ERK1/2-MAPK, STAT3-IL8-VEGF pathways, etc. [3, 10]. This evidence concerns the gene CRK and cancer.