1K1C surgery-induced hypertension increased CGRP binding in wt as well as in CLR-tg mice (mean of all investigated brain structures shown in Fig 4: wtnormorensive: 158.2 ±55.7 nCi/g, CLR-tgnormotensive: 251.1 ±43.3 nCi/g, wthypertensive: 225.9 ±48.1 nCi/g, CLR-tghypertensive: 390.6 ±59.9 nCi/g). The gene discussed is DCLK3; the disease is Hypertension.