As shown in Table 2, there were significant differences in age, education, physical activity, prehypertension, hypertension, DM, WC, BMI, SDP, DBP, Scr, serum glucose, plasma insulin, TG, HDLC, TC, and LDLC in females; the upper VAI quartile participants exhibited higher ages, prevalence of prehypertension, prevalence of hypertension, DM, SBP, DBP, Scr, serum glucose, plasma insulin, TG, TC, and LDLC, and lower HDLC and physical activity levels, compared with the lower VAI quartile subjects, among females. The gene discussed is INS; the disease is diabetes mellitus.