HLA-B and AIDS: One of these studies reported the predicted peptide-binding repertoires for four human class I alleles, finding a rank hierarchy from the extremely fastidious HLA-B*57:01 to HLA-B*27:05 to HLA-B*07:02 to the highly promiscuous HLA-B*35:01, that correlated directly with progression from HIV infection to AIDS (Kosmrlj et al., 2010).