CD163 and in situ carcinoma: The geometric mean (GM) values of the sCD163 ratio was significantly increased for the patients with RRMS: 1.36 fold (95%CI: 1.17–1.59; p<.001), CIS: 1.33 fold (95%CI: 1.07, 1.65; p = 0.010), and especially PPMS: 1.57 fold (95%CI: 1.23–1.97; p<0.001).