We have previously reported that Th cells are involved in the pathogenesis of the disease process in OLP and the potential antigen recognized by these Th cells was derived from the basal epithelial cells in OLP lesions.3 In this study, CD3+ and CD4+ T cells were mainly distributed throughout both the connective tissue papillae and the lamina propria from both GS and OLP patients. The gene discussed is CD4; the disease is oral lichen planus.